Molecular and Cellular Mechanisms in Disease
نویسندگان
چکیده
منابع مشابه
O14: Cellular and Molecular Mechanisms of Spinal Cord Trauma
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Introduction: Spinal cord injury (SCI) following traumatic events is associated with the limited therapeutic options and sever complications, which can be partly due to inflammatory response. Therefore, this study aims to explore the role of inflammation in spinal cord injury. The findings showed that the pathological conditions of nervous system lead to activation of microglia, astrocyte, neut...
متن کاملo14: cellular and molecular mechanisms of spinal cord trauma
the prevalence of spinal cord injury (sci) is about 2.5 million in the worldwide and more than 130,000 new injuries reported each year. regeneration in the cns versus the pns is very different from the other tissues and many factors can prevent regeneration in pns and specially cns. previous researches demonstrated that regeneration of cns can inhibit by inhibitory molecules and glial scar. the...
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Sickle cell disease (SCD) is a global public health disorder that affects millions of people across the globe. It is a monogenic disorder caused by an A-toT point mutation in the β-globin gene that produces abnormal hemoglobin S (Hb S), which polymerizes in the deoxygenated state, resulting in physical deformation or sickling of erythrocytes. Sickle erythrocytes promote vaso-occlusion and hemol...
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Graft-versus-host disease is a complication in patients undergoing hematopoietic stem cell transplantation. Graft-versus-host disease includes acute graft-versus-host disease and chronic graft-versus-host disease. Host APCs (e.g., dendritic cells and macrophages), effector T cells (e.g., Th1, Th17, and abnormal Th17:regulatory T cell ratio), B cells, and NK cells are implicated in graft-versus-...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1977
ISSN: 0021-9746
DOI: 10.1136/jcp.30.3.296-b